Bridging the gap between oncology clinical trials and real-world data: evidence on replicability of efficacy results using German claims data

Abstract Aims: Using German claims, the authors replicated the CHAARTED trial in metastatic hormone-sensitive prostate cancer. Methods: The authors identified metastatic hormone-sensitive prostate cancer patients replicating the inclusion/exclusion criteria of CHAARTED. Patients treated...

Advancing digital health applications: priorities for innovation in real-world evidence generation

Ariel D Stern 1, Jan Brönneke 2, Jörg F Debatin 2, Julia Hagen 2, Henrik Matthies 2, Smit Patel 3, Ieuan Clay 4, Bjoern Eskofier 5, Annika Herr 6, Kurt Hoeller 7, Ashley Jaksa 8, Daniel B Kramer 9, Mattias Kyhlstedt 10, Katherine T Lofgren 11, Nirosha Mahendraratnam 12, Holger Muehlan 13, Simon Reif 14, Lars Riedemann 15, Jennifer C Goldsack 3 Affiliations 1Technology and Operations Management...