March 17, 2022 06:30 ET | Source: Centogene NV
- In November 2019, CENTOGENE first announced the signing of a data access and collaboration agreement to discover and validate novel genetic and biochemical targets for the potential development of new therapies for rare diseases
- New research phase aims to substantiate earlier results and further leverage CENTOGENE’s Bio/Databank to evaluate rare genetic causes of neurodegenerative diseases
ROSTOCK, Germany and BERLIN, March 17, 2022 (GLOBE NEWSWIRE) — Centogene N.V. (Nasdaq: CNTG), a commercial-stage company focused on generating data-driven insights to diagnose, understand, and treat rare diseases, announced an expansion of the Company’s data access and collaboration agreement with Pfizer Inc. The initial agreement, which granted Pfizer access to data of interest from CENTOGENE’s Bio/Databank, was established in 2019 to advance the discovery and validation of novel genetic targets as candidates for the development of new therapies for rare diseases.
A new collaborative research project has now been initiated, which may be used to validate rare genetic causes of neurodegenerative diseases as potential targets for specific diseases. Data will be generated based on an existing cohort of patient samples from CENTOGENE’s Bio/Databank.
Dr. Patrice Denèfle, Chief Scientific Officer at CENTOGENE, said, “Establishing an additional collaborative research project with Pfizer underscores the value we believe our Bio/Databank may bring to data-driven discovery in rare diseases R&D. With our Bio/Databank, extensive cohorts from clinical studies, and diverse global diagnostic footprint, CENTOGENE is uniquely positioned to discover potential roadmaps for neurodegenerative diseases that may be linked to rare genetic factors. This new phase in our research collaboration project is a milestone achievement for innovative data-driven drug discovery and development that may help in delivering breakthrough treatments to patients.”
CENTOGENE’s unique Bio/Databank integrates relevant structured and unstructured patient-consented data, including clinical information, health records, and multiomic data, including genetic, transcriptomic, proteomic, and metabolomic insights. It also includes longitudinal data, such as biomarkers and patient recorded outcomes, as well as diagnostic workflow data. Individual-level data is managed, protected, and shared in compliance with international data privacy regulations.
About CENTOGENE
CENTOGENE engages in diagnosis and research around rare diseases transforming real-world clinical, genetic, and multiomic data to diagnose, understand, and treat rare diseases. Our goal is to bring rationality to treatment decisions and to accelerate the development of new orphan drugs by using our extensive rare disease knowledge and data. CENTOGENE has developed a global proprietary rare disease platform based on our real-world data repository of over 600,000 patients representing over 120 different countries.
The Company’s platform includes epidemiologic, phenotypic, and genetic data that reflects a global population, as well as a biobank of patients’ blood samples and cell cultures. CENTOGENE believes this represents the only platform focused on comprehensive analysis of multi-level data to improve the understanding of rare hereditary diseases. It allows for better identification and stratification of patients and their underlying diseases to enable and accelerate discovery, development, and access to orphan drugs. As of December 31, 2020, the Company collaborated with over 30 pharmaceutical partners.
Source: https://www.globenewswire.com/news-release/2022/03/17/2405036/0/en/CENTOGENE-Announces-Expansion-of-Data-Access-and-Collaboration-Agreement-With-Pfizer.html